Elderly people with hardening of the arteries are more likely to have brain plaques associated with Alzheimer's disease, a new study says.
The study included 91 people, average age 87, who did not have dementia
and underwent scans to assess any beta-amyloid plaques in their brains.
The degree of stiffness of their arteries was checked about two years
later.
Half of the participants had brain plaques and these
people were more likely to have high systolic blood pressure (the top
number that shows the amount of pressure on blood vessels when the heart
beats), higher average blood pressure and greater arterial stiffness.
For every unit increase in arterial stiffness,
people were twice as likely to have beta-amyloid plaques in the brain.
Arterial stiffness was highest in people who had both amyloid plaques
and lesions in their brain's white matter, according to the study
published online Oct. 16 in the journal Neurology.
"This is more evidence that cardiovascular health
leads to a healthy brain," study author Timothy Hughes, of the
University of Pittsburgh, said in a journal news release.
He noted that the link between arterial stiffness
and brain plaques did not change when regular resting blood pressure was
taken into account.
"This study adds to growing evidence that hardening
of the arteries is associated with cerebrovascular disease that does not
show symptoms. Now we can add Alzheimer's-type lesions to the list,"
Hughes said.
Although the study found an association between
hardening of the arteries and levels of Alzheimer's-related brain plaque
in older adults, it did not establish cause and effect.
Source: Health Day News
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