Just by increasing their physical activity, people with type 2 diabetes can lose fat that accumulates in the liver and abdomen and lower their risk of heart problems.
Doctors recommend that people diagnosed with diabetes get regular
exercise, since physical activity can keep them at a healthy weight and
help organs like the lungs, liver and heart to work at their best. But
the details of how breaking a sweat influences the different fat
deposits around the body are not so clear. There is increasing evidence,
for example, that buildup of fat in the abdomen and deep in organs such
as the liver and heart, can be more harmful than fat deposited just
under the skin, since the more deeply embedded fat, known as visceral fat, releases hormones and other compounds that can affect how efficiently the body breaks down calories. But because most studies involving exercise
also allow volunteers to change their diet, pinpointing how physical
activity changes fat depots in the body has been hard to document.
To gather more information on this relationship, researchers from
Leiden University Medical Center in the Netherlands turned to detailed
MRI images to study 12 middle-aged diabetic patients both before and
after they participated in a six month program of moderate-intensity
exercise. The volunteers exercised for 3.5 hours to 6 hours a week, and
participated in two endurance and two resistance training sessions,
finishing up with a 12-day hiking expedition. Throughout the study,
however, they were told not to change their diet and eating habits.
After the training, the researchers found that the participants’
heart functions remained relatively unchanged, but the second round of
MRI scans revealed significant decreases in the volume of fat that
surrounded the heart and lungs as well as in their abdominal area.
In a statement, the study’s senior author, Dr. Hildo J. Lamb from the
Department of Radiology at Leiden University Medical Center said, “The
liver plays a central role in regulating total body fat distribution.
Therefore, reduction of liver fat content and visceral fat volume by
physical exercise are very important to reverse the adverse effects of
lipid accumulation elsewhere, such as the heart and arterial vessel
wall.”
Because the study did not follow the patients for an extended period
of time, the changes in fat distribution did not translate into
measurable changes in heart function, but the researchers hope that with
additional follow up, that would occur. And while the study was small,
the results were encouraging since the participants were able to lower
their levels of harmful fat simply by becoming more physically active —
without changing their diet.
The findings also give researchers new insight into how different types
of fat in the body contribute to diseases such as diabetes and heart
disease. Imaging techniques like MRI, for example, might one day
identify people at greater risk of developing the insulin resistance
that heralds diabetes, or future heart problems by revealing fat depots
wrapped around organs. That in turn could help more people to address
their risk factors and prevent health problems by exercising more, or
changing their diet, or both.
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